Scientific studies show: NEUROvitalis works

The Department of Medical Psychology | Neuropsychology and gender studies of the Medical Faculty and University Hospital Cologne as well as the Clinic and Polyclinic for Neurology of the University Hospital Cologne have proven in many studies since 2009 that NEUROvitalis is effective.

NEUROvitalis scientific results

The table shows an example of the effect size of the NEUROvitalis treatment during a study from 2011. The more stars in a column, the more effective the therapy was in this area.

Key:
H w/o T: Healthy without therapy, H CT: Healthy non-specific control training, H NV: Healthy NEUROVitalis
MCI CT: Mild Cogn. Impairments control training, MCI NV: Mild Cogn. Impairments NEUROVitalis, AD NV: Alzheimer’s dementia NEUROVitalis

References to literature and publications on the NEUROvitalis program

Folkerts AK, Dorn M, Roheger M, Maassen M, Koerts J, Tucha O, Altgassen M, Sack AT, Smit D, Haarmann L, Kalbe E (eingereicht).
Cognitive stimulation in individuals with Parkinson’s disease dementia living in a specialized Parkinson care unit: A randomized cross-over pilot study. Parkinson’s Disease.

Kalbe E, Roheger M, Paluszak K, Meyer J, Becker J, Fink GR, Kukolja J, Rahn A, Szabados F, Wirth B, Kessler J (in Vorbereitung).
Cognitive training with and without additional physical activity in healthy older adults: effects of a randomized controlled trial on cognition one year after intervention.

Roheger M, Kessler J, Kalbe E (in Revision).
Cognitive Training in Healthy Older People: A Scientifically based Structured Training yields best Results, and the ApoE4 State and Baseline Level influence Training Benefits. Frontiers in Human Neuroscience.

Middelstädt J, Folkerts AK, Blawath S, Kalbe E (2016).
Cognitive Stimulation for People with Dementia in Long-term Care Facilities: Baseline cognitive level predicts cognitive gains, moderated by depression. Evidence from a Randomized Controlled Trial. Journal of Alzheimer’s disease, 54, 253-68.

Petrelli A, Kaesberg S, Barbe MT, Timmermann L, Rosen J, Fink GR, Kessler J, Kalbe E (2015).
One-year follow-up of cognitive training in Parkinson’s disease. European Journal of Neurology, 22, 640-647.

Rahe J, Becker J, Fink GR, Kessler J, Kukolja J, Rahn A, Rosen JB, Szabados F, Wirth B, Kalbe E (2015).
Cognitive training with and without additional physical activity in healthy older adults: cognitive effects, neurobiological mechanisms, and prediction of training success. Frontiers in Aging Neuroscience, 7, 187.

Rahe J, Liesk J, Rosen JB, Petrelli A, Kaesberg S, Onur OA, Kessler J, Fink GR, Kalbe E (2015).
Sex differences in cognitive training effects of patients with amnestic mild cognitive impairment. Aging, Neuropsychology, and Cognition, 22 , 620-638.

Rahe J, Petrelli A, Kaesberg S, Fink GR, Kessler J, Kalbe E (2015).
Effects of cognitive training with additional physical activity compared to pure cognitive training in healthy older adults. Clinical Interventions in Aging, 19, 297-310.

Liesk J, Hartogh T, Kalbe E (2014).
Kognitive Stimulation und Musikintervention bei stationär versorgten Menschen mit Demenz.  Eine Pilotstudie, Probleme & Perspektiven. Zeitschrift für Gerontologie und Geriatrie, 48, 275-281.

Petrelli A, Kaesberg S, Kessler J, Barbe MT, Fink GR, Timmermann L, Kalbe E (2014).
Effects of cognitive training in patients with Parkinson´s disease: a randomized controlled trial. Parkinsonism & Related Disorders, 20, 1196-1202.

Rahe J, Petrelli A, Kaesberg S, Baller G, Kessler J, Kalbe E (2012).
Kognitive Trainingseffekte des neuropsychologischen Programms NEUROvitalis in Kombination mit physischer Aktivität. Neurologie & Rehabilitation, 18, 187.

Kalbe E, Kaesberg S, Petrelli A, Baller G, Fink GR & Kessler J (2011).
Strukturiertes Training NEUROvitalis versus Hirnjogging bei Patienten mit leichten kognitiven Störungen und gesunden Älteren: eine randomisierte, kontrollierte Studie.  Zeitschrift für Neuropsychologie, 22, 194.

Müller K, Kaesberg S, Petrelli A, Kalbe E, Baller G, Sack AT, Kessler J (2011).
Non-pharmakologische Intervention bei Patienten mit Multipler Sklerose – Effekte des neuropsychologischen Trainings NEUROvitalis. Zeitschrift für Neuropsychologie, 22, 228.

Petrelli A, Kaesberg S, Barbe MT, Timmermann L, Kessler J, Baller G, Fink GR, Kalbe E (2011).
Kognitives Basisniveau und Antrieb als Prädiktoren für den Trainingserfolg von Patienten mit idiopathischem Parkinson-Syndrom im neuropsychologischen Gruppentraining NEUROvitalis. Zeitschrift für Neuropsychologie, 22, 230.

Kaesberg S, Mayer A, Schlegel M, Baller G, Fink G, Kessler J, Kalbe E (2010).
NEUROvitalis®: Effekte eines neuen neuropsychologischen Trainings bei gesunden Älteren sowie bei Patienten mit Mild Cognitive Impairment und beginnender Alzheimer Demenz. Zeitschrift für Neuropsychologie, 21, 221.

Kaesberg S, Kalbe E, Mayer A, Baller G, Sack A, Kessler J (2009).
NEUROvitalis®: effects of a new neuropsychological training in healthy elderly individuals as well as patients suffering from Mild Cognitive Impairment and early-stage Alzheimer’s Disease. Alzheimer’s and Dementia, 5, 332.

Kalbe E, Kaesberg S, Mayer A, Schlegel M, Baller G, Fink GR, Kessler J (2009).
NeuroVitalis®: Effekte eines neuen neuropsychologischen Trainings bei Patienten mit leichten kognitiven Störungen und Patienten mit Alzheimer Demenz. Aktuelle Neurologie, 36, 149.

PDF IconA literature list (with abstracts) can be found here.